Preheat oven to 350 degrees. Spray a 9x5 inch loaf pan with non-stick cooking spray. Set aside.
In a large bowl, whisk together flour, baking powder, baking soda and salt. Set aside.
In the bowl of a stand mixer fitted with a paddle attachment, beat butter and sugar on medium speed until light and fluffy. Add eggs, one at a time until well blended. Add sour cream, vanilla and lemon zest. Beat until smooth, scraping down the bowl when necessary.
With the mixer on low, gradually add the flour mixture reserving one tablespoon to toss the blueberries with. Remove the bowl from the mixer, and carefully fold the blueberries into the mixture with a rubber spatula. Spread the batter into the prepared pan, smoothing the top. Sprinkle the top with granulated sugar, if desired.
Bake for 1 hour and 15 minutes or until toothpick inserted in center of loaf comes out clean. If loaf is browning too quickly, tent with a piece of foil. (I tented mine around the 50-55 minute mark.
Cool in pan for 15 minutes. Release from pan and let cool on wire rack.